| Field | Specification |
|---|---|
| Target | |
| Alternative names | Sell; Lnhr; Ly-22; L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; CD antigen CD62L |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
L-Selectin (SELL) is a biological molecule commonly studied in stem cells research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: P30836
Biological context
Researchers often monitor L-Selectin in serum, plasma, and tissue homogenates to better understand themes such as mechanistic biology studies, biomarker-focused profiling, and disease-model research. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in L-Selectin may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, complementary pathway markers and controls appropriate to the biological model) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, L-Selectin may also appear under names such as Sell and Lnhr. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that L-Selectin participates in.
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Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to "Composite" Blast
Stanislav I. Svetlov et al,Frontiers in Neurology,2012
