| Field | Specification |
|---|---|
| Target | |
| Alternative names | Mif ELISA Kit; Macrophage migration inhibitory factor ELISA Kit; MIF ELISA Kit; EC 5.3.2.1 ELISA Kit; Glutathione-binding 13 kDa protein ELISA Kit; L-dopachrome isomerase ELISA Kit; L-dopachrome tautomerase ELISA Kit; EC 5.3.3.12 ELISA Kit; Phenylpyruvate tautomerase ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Macrophage Migration Inhibitory Factor (MIF) is a biological molecule commonly studied in immunology research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: P30904
Biological context
Researchers often monitor Macrophage Migration Inhibitory Factor in serum, plasma, and tissue homogenates to better understand themes such as innate and adaptive immune responses, cytokine signaling networks, and host–pathogen interactions. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Macrophage Migration Inhibitory Factor may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, cytokines, chemokines, acute-phase proteins, and immune-cell activation markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Macrophage Migration Inhibitory Factor may also appear under names such as Mif and Macrophage migration inhibitory factor. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Macrophage Migration Inhibitory Factor participates in.
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The Role of Macrophage Migration Inhibitory Factor in Remote Ischemic Conditioning Induced Hepatoprotection in A Rodent Model of Liver Transplantation
Emontzpohl C, et al,Canadian Journal of Cardiology,2019
Paralemmin-3 contributes to lipopolysaccharide-induced inflammatory response and is involved in lipopolysaccharide-Toll-like receptor-4 signaling in alveolar macrophages
Chen XX.et al,Int J Mol Med,2017
The potential role of polymethyl methacrylate as a new packaging material for the implantable medical device in the bladder
Kim SJ.et al,Biomed Res Int.,2015
Gender differences in oesophageal mucosal injury in a reflux oesophagitis model of rats
Tomohiro Masaka et al,GUT,2013
