| Field | Specification |
|---|---|
| Target | |
| Alternative names | Nfkb1 ELISA Kit; Nuclear factor NF-kappa-B p105 subunit ELISA Kit; DNA-binding factor KBF1 ELISA Kit; EBP-1 ELISA Kit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] ELISA Kit; Fragment ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Nuclear factor-kappa B(NF-κB) (NFKB1) is a biological molecule commonly studied in cell biology research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q63369
Biological context
Researchers often monitor Nuclear factor-kappa B(NF-κB) in serum, plasma, and tissue homogenates to better understand themes such as signal transduction pathways, cell cycle control, and stress-response programs. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Nuclear factor-kappa B(NF-κB) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, phosphorylation-dependent signaling nodes, stress markers, and organelle proteins) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Nuclear factor-kappa B(NF-κB) may also appear under names such as Nfkb1 and Nuclear factor NF-kappa-B p105 subunit. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Nuclear factor-kappa B(NF-κB) participates in.
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