| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tfpi ELISA Kit; Tissue factor pathway inhibitor ELISA Kit; TFPI ELISA Kit; Extrinsic pathway inhibitor ELISA Kit; EPI ELISA Kit; Lipoprotein-associated coagulation inhibitor ELISA Kit; LACI ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, cell culture supernates, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Tissue factor pathway inhibitor (TFPI) is a biological molecule commonly studied in cardiovascular research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q02445
Biological context
Researchers often monitor Tissue factor pathway inhibitor in serum, plasma, cell culture supernates, and tissue homogenates to better understand themes such as vascular biology and endothelial function, cardiac remodeling and injury responses, and thrombosis and hemostasis. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Tissue factor pathway inhibitor may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, endothelial markers, coagulation-related proteins, and cardiac injury markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Tissue factor pathway inhibitor may also appear under names such as Tfpi and Tissue factor pathway inhibitor. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Tissue factor pathway inhibitor participates in.
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Procoagulant and Fibrinolytic Activity after Polytrauma in Rat
Wu X. et al,Am J Physiol Regul Integr Comp Physiol,2015
