| Field | Specification |
|---|---|
| Target | |
| Alternative names | TREM-2, Trem2a, Trem2b, Trem2c, triggering receptor expressed on monocytes 2|triggering receptor expressed on myeloid cells 2a |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
triggering receptor expressed on myeloid cells 2(TREM2) is a biological molecule commonly studied in immunology research. Immunoglobulins are antibody proteins central to humoral immunity and antigen-specific responses.
Biological context
Researchers often monitor triggering receptor expressed on myeloid cells 2(TREM2) in serum, plasma, and tissue homogenates to better understand themes such as innate and adaptive immune responses, cytokine signaling networks, and host–pathogen interactions. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in triggering receptor expressed on myeloid cells 2(TREM2) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, cytokines, chemokines, acute-phase proteins, and immune-cell activation markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, triggering receptor expressed on myeloid cells 2(TREM2) may also appear under names such as TREM-2, Trem2a, Trem2b, Trem2c, triggering receptor expressed on monocytes 2 and triggering receptor expressed on myeloid cells 2a. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that triggering receptor expressed on myeloid cells 2(TREM2) participates in.
Can’t Find What You’re Looking For? We can help you source the best match or customize an ELISA solution for your study. Options may include alternative target synonyms, different species reactivity, sample type/matrix compatibility (serum/plasma/lysate/supernatant), assay format (sandwich/competitive), sensitivity/range, detection chemistry (colorimetric/fluorescent/chemiluminescent), plate format (pre-coated/uncoated, strips vs full plate), and bulk or custom packaging. Click Talk to a Scientist to submit a request form, email us at support@biohippo.com, or explore our Research Services for additional support. Our team will be in contact with you shortly.
“Combo” Multi-Target Pharmacological Therapy and New Formulations to Reduce Inflammation and Improve Endogenous Remyelination in Traumatic Spinal Cord Injury
M Moretti,Cells,2023
Ameliorative effects of glycine in an experimental nonalcoholic steatohepatitis and its correlation between TREM-1 and TREM-2
Zhang-Feng Dou.et al,Am J Transl Res,2016
