| Field | Specification |
|---|---|
| Target | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A recombinant partial protein sequence (within amino acids 273-407) from the human protein was used as the immunogen for the recombinant Mesothelin antibody. |
| Purity | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Overview
Recombinant Mesothelin Antibody is an antibody targeting Mesothelin. Host: Rabbit. Monoclonal. Clone: MSLN/8391R. Format: Purified. Applications: IHC-P, WB.
Key elements and design rationale
- Target: Mesothelin.
- Immunogen: A recombinant partial protein sequence (within amino acids 273-407) from the human protein was used as the immunogen fo….
- Species reactivity: Human.
- Localization: Cell surface, Secreted.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
