| Field | Specification |
|---|---|
| Mfr No | |
| Accession Number | |
| Alternative Names | Interferon Alpha-2; IFN-Alpha-2; Interferon Alpha-A; LeIF A; IFNA2 |
| Endotoxin Level | |
| Expression System | |
| Form | Lyophilized |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Reconstitution | |
| Shipping | |
| Species | |
| Storage | |
| Target |
Background
IFN-ALPHA is a target studied in immunology & inflammation research. The sections below provide general scientific background to support interpretation-focused decision making.
- Gene/target: IFN-ALPHA
- Protein name: IFN alpha2
- Alternative names: Interferon Alpha-2, IFN-Alpha-2, Interferon Alpha-A
- Accession: P01573
- Species context: Mouse
Sequence/region note: Recombinant constructs are often produced as defined fragments or domains. This product corresponds to an expressed region annotated as Cys24-Glu190, which may represent a specific portion of the full-length protein used for controlled studies.
Biological role and pathway context
IFN-ALPHA is commonly discussed in the context of immune communication, where soluble mediators and surface molecules coordinate activation, trafficking, and effector responses. Functional outcomes can depend on receptor expression, local microenvironment, and the presence of other cytokines or co-stimulatory signals.
In Immunology & Inflammation research, IFN-ALPHA is often discussed within themes such as immune signaling networks, cytokine and receptor communication, cell trafficking and inflammatory regulation. These themes can help frame interpretation of molecular measurements in relation to broader biological programs.
In pathway context, immune targets are often interpreted alongside upstream stimuli and downstream signaling readouts (for example, transcriptional programs and phosphorylation-dependent signaling states). Because immune activation is dynamic, timing and sample composition can strongly influence observed changes.
When building hypotheses, researchers commonly consider related ligands/receptors in the same family, downstream adaptors, and cytokine/chemokine networks that shape cell recruitment and activation states.
Expression and regulation
Expression of IFN-ALPHA can be regulated at multiple levels, including transcriptional control, mRNA stability, translation, and protein turnover. Many targets also exhibit context-dependent expression across tissues or model systems and may respond dynamically to stress, growth cues, immune stimulation, or metabolic state. When comparing datasets, consider species, cell type, stimulus, and time course.
Isoforms and molecular forms
Many proteins exist as alternative isoforms or processed forms, and post-translational modifications (for example, phosphorylation, glycosylation, acetylation, or proteolytic processing) can alter localization, interactions, or activity. When interpreting results involving IFN-ALPHA, consider whether studies distinguish full-length protein from specific domains or fragments, and whether modification states are relevant to the biological question.
Why it matters in research
- Pathway interpretation: helps connect molecular changes to network-level hypotheses in immunology & inflammation studies.
- Comparative analysis: supports cross-condition or cross-model comparisons when nomenclature and context are aligned.
- Systems context: often interpreted alongside related pathway components to distinguish direct effects from secondary changes.
Disease and process relevance
Depending on the target, published studies may report associations between IFN-ALPHA and disease mechanisms or physiological processes. Such associations are typically context dependent and are best interpreted alongside complementary markers and functional readouts, rather than as standalone evidence.
What is the purity of Recombinant Mouse IFN alpha2 (Mouse)?
How should Recombinant Mouse IFN alpha2 (Mouse) be stored?
What expression system was used to produce this protein?
What is the molecular weight of this protein?
What are the shipping conditions?
Is this protein approved for clinical or in vitro diagnostic use?
Can I request a custom size, tag variant, or formulation?
Can’t Find What You’re Looking For? We can help you source the best match or customize a recombinant protein solution for your study. Options may include species (human/mouse/rat), protein region/domain (full-length vs fragment), tag or label (His/GST/FLAG/biotin/fluorescent), expression system (E. coli/HEK293/insect), purity grade, formulation (buffer, carrier-free, glycerol-free), activity/functional validation (binding or enzymatic assays), endotoxin level (low-endotoxin for cell-based work), mutants/variants (point mutations, isoforms), and bulk or custom packaging. Click Talk to a Scientist to submit a request form, email us at support@biohippo.com, or explore our Research Services for additional support. Our team will be in contact with you shortly.
