| Field | Specification |
|---|---|
| Alternative names | Retinyl β-D-glucoside |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C26H40O6 |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Retinyl glucoside, also known as retinyl β-D-glucoside, is a lipid β-D-glucoside of retinol and serves as a substrate for broad-spectrum β-glucosidase. It can be hydrolyzed by guinea pig hepatocyte cytosolic and membrane-associated β-glucosidases, as well as by almond β-glucosidase, to release retinol and glucose, but it is not hydrolyzed by human placental glucocerebrosidase. It can be used in research on Gaucher's disease[1]. It is supplied as a yellow to brown solid (C26H40O6, MW 448.59).
Physical & Chemical Properties
| CAS Number | 136778-12-6 |
|---|---|
| Molecular Formula | C26H40O6 |
| Molecular Weight | 448.59 g/mol |
| Appearance | Solid |
| Color | Yellow to brown |
| SMILES | CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)=C(C)CCC1 |
| Signaling Pathway | Metabolic Enzyme/Protease |
| Storage | -20°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
In 0.1 M sodium acetate (pH 5.5), almond β-glucosidase can hydrolyze Retinyl glucoside (60 min), releasing retinol and glucose in nearly equimolar amounts, with a glucose/retinol molar ratio of 0.99[1]. Guinea pig hepatocellular cytosolic β-glucosidase and membrane-associated TX-100 β-glucosidase can also hydrolyze Retinyl glucoside (60 min) in 0.2 M Sodium Citrate (pH 6.0)[1]. Human placental glucocerebrosidase does not hydrolyze Retinyl glucoside (1 h) in 0.1 M sodium acetate (pH 5.5) containing TdC[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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