| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C20H19N5O2S |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
RIPK1-IN-16 is an orally active, potent inhibitor of RIPK1 that suppresses excessive inflammation by blocking RIPK1-mediated necroptosis in vivo. It protects mice from TNF-induced systemic inflammatory response syndrome and sepsis[1]. It has a molecular formula of C20H19N5O2S and a molecular weight of 393.46 g/mol.
Physical & Chemical Properties
| CAS Number | 2561431-77-2 |
|---|---|
| Molecular Formula | C20H19N5O2S |
| Molecular Weight | 393.46 g/mol |
| SMILES | CN1C2=CC=CC=C2OC[C@H](NC(C3=NNC(CC4=CC=CC=C4)=N3)=O)C1=S |
| Signaling Pathway | Apoptosis |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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