| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C93H141N11O23 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth. It is supplied as a white to light yellow solid (C93H141N11O23, MW 1781.17) at 98.41% purity.
Physical & Chemical Properties
| CAS Number | 2250059-52-8 |
|---|---|
| Molecular Formula | C93H141N11O23 |
| Molecular Weight | 1781.17 g/mol |
| Purity | 98.41% |
| Appearance | Solid |
| Color | White to light yellow |
| SMILES | NC1=C2C(C3=CC4=CC(O)=CC=C4N3)=NN(C2=NC=N1)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN5C=C(N=N5)CCCCO[C@H]6[C@@H](C[C@@H](CC6)C[C@H]([C@@]7([H])OC([C@@]8([H])N(CCCC8)C(C([C@@]9(O[C@](CC[C@H]9C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C([C@@H]([C@@H](/C(C)=C/[C@H](C(C7)=O)C)O)OC)=O)C)C)OC)O)=O)=O)=O)C)OC)=O |
| Signaling Pathway | PI3K/Akt/mTOR |
| Solubility | In Vitro: DMSO: 100 mg/mL (56.14 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | -20°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 100 mg/mL (56.14 mM) | requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); sealed storage, away from moisture and light; avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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