(RS)-AMPA hydrobromide

Product details

• Chemical name: 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid;hydrobromide.
• Also known as: AMPA, (+/-)-AMPA hydrobromide
• CAS number: 171259-81-7
• Molecular formula: C7H11BrN2O4.
• Purity: >95%
• Concentration: 0.1-100 µM.
• Form: Lyophilized powder.
• Solubility: 50 mM in H2O. Centrifuge all product preparations before use (10,000 x g for 1 min).
• Reconstitution: 50 mM in H2O. Centrifuge all product preparations before use (10,000 x g for 1 min).
• Shipping: Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
• Target: AMPA receptors
• Source: Synthetic
• Activity: (RS)-AMPA is a selective AMPA receptor agonist1.
• Alternative names: AMPA, (+/-)-AMPA hydrobromide

Scientific background

Glutamate is the main excitatory neurotransmitter in the CNS. It is also involved in a variety of pathological conditions including epilepsy. Glutamate binds to a number of different receptor types such as the AMPA, kainate and NMDA receptors that relay its excitatory activity.(RS)-AMPA is a synthetic AMPA receptor agonist. It has an effective concentration of 0.1-100 µM. RS-AMPA selectively binds to AMPA receptors over the other types of glutamate receptors. RS-AMPA was found to elicit feeding behavior in a rat model while RS-AMPA's enantiomer did not produce similar results1.

Lead time: 1-2 Business Days

Country of origin: Israel/IL

Applications key

Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.

Bioassay tested: Yes

Cited application(s)

Electrophysiology

• SDS (PDF)

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