rVSV pseudotyped MARV GP

What it means: This product is a pseudotyped virus — a non-replicating particle that displays authentic viral surface antigens without the risks of live virus.

Why it matters:

• A pseudotyped virus lets you work with native viral proteins in their correct conformation while avoiding handling of replicating virus.
• This substantially lowers the biosafety burden for neutralisation, entry and antibody-evaluation studies.
• Because the antigens are presented natively, results translate well to studies of the corresponding live pathogen.

How to interpret here: This pseudotyped virus presents Marburg Virus antigens, giving a safe and representative tool for in-vitro research.

Tip: Confirm the required biosafety level with your institutional biosafety officer before beginning work.

What it means: The expression system is the host platform used to produce the particle. This product is generated in HEK-293T cells.

Why it matters:

• Production in HEK-293T cells shapes the glycosylation and assembly of the displayed viral antigens.
• This influences how faithfully the particle reproduces the native virus surface in binding and neutralisation assays.
• The platform also affects yield, purity and batch consistency.

How to interpret here: This particle is produced in HEK-293T cells; expect antigen presentation characteristic of that system.

Tip: Match the expression system to the structural fidelity your assay requires.

What it means: The target pathogen is the virus whose surface antigens this particle displays — Marburg Virus.

Why it matters:

• Antigen identity and strain define which antibodies, sera and vaccines the particle can be used to evaluate.
• Strain matching is essential for meaningful neutralisation and cross-reactivity research.
• Documented pathogen provenance supports comparison across neutralisation panels and studies.

How to interpret here: This particle represents Marburg Virus (Angola strain); align it with the strains in your neutralisation panel.

Tip: Choose a particle strain that matches the antibodies or sera you intend to test.

What it means: Storage states the conditions required to keep the particle stable and functional: -80°C.

Why it matters:

• Correct storage preserves particle integrity and the native display of viral antigens.
• Freeze-thaw cycling can disrupt particles and degrade assay performance and reproducibility.
• Stable storage protects the reagent across repeated neutralisation runs.

How to interpret here: Store this product exactly as stated (-80°C) on receipt.

Tip: Aliquot immediately and keep freeze-thaw cycles to a minimum.