S-MGB-234 TFA

SKU:BHB21901221
Overview
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S-MGB-234 TFA (CAS 1970223-54-1) is a bioactive small molecule. Relevant to Cell Cycle/DNA Damage and Anti-infection research. Molecular formula C34H34F6N8O8, molecular weight 796.67 g/mol.
CAS Number 1970223-54-1
Molecular Weight 796.67 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-145287A-50MG 50 mg
HY-145287A-100MG 100 mg
HY-145287A-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 1970223-54-1
Applications
  • Functional Assay (In Vitro)
Molecular weight 796.67
Molecular formula C34H34F6N8O8
SMILES O=C(C1=CC=C(/C=C/C2=CC=C(OC)C=C2)N=C1)NC3=CN(C)C(C(NC4=CN(C)C(C(NCCC(N)=N)=O)=C4)=O)=C3.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-145287A
Main SKU BHB21901221
Bioactive Small Molecules

Compound Overview

S-MGB-234 TFA is a minor groove binder used for research on African Animal Trypanosomiasis (AAT). It exhibits excellent in vitro activity against the primary AAT pathogens Trypanosoma congolense and Trypanosoma vivax, without cross-resistance to current diamidine-active molecules, and is not internalized via the transporters used by diamidines[1]. It has a molecular formula of C34H34F6N8O8 and a molecular weight of 796.67 g/mol.

Physical & Chemical Properties

CAS Number 1970223-54-1
Molecular Formula C34H34F6N8O8
Molecular Weight 796.67 g/mol
SMILES O=C(C1=CC=C(/C=C/C2=CC=C(OC)C=C2)N=C1)NC3=CN(C)C(C(NC4=CN(C)C(C(NCCC(N)=N)=O)=C4)=O)=C3.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Signaling Pathway Cell Cycle/DNA Damage; Anti-infection
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Giordani F, et al. Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model [published correction appears in J Med Chem. 2021 Dec 23;64(24):18236]. J Med Chem. 2019;62(6):3021-3035.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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