Safinamide

SKU:BHB11900413
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Safinamide is a research-grade small-molecule inhibitor of MAO-B supporting Neuroscience and Neurodegeneration research. Supplied as a white powder with >98% purity (CAS 133865-89-1, MW 302.3) dissolvable in DMSO; store at -20°C. For research use only.
Cas No. 133865-89-1
Molecular Formula C17H19FN2O2
Purity >98% (HPLC); NMR (Conforms)
Application Notes MAO-B Inhibitor
Options selector
Catalog no. Size
SIH-625-5MG 5 mg
SIH-625-25MG 25 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 25 mg, 5 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-625
Activity
  • Inhibitor
Alternative Names (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; FCE-26743; PNU-151774E; NW-1015
Cas No. 133865-89-1
Form White powder
Molecular Weight 302.3
Product Type
  • Biochemicals
  • Small Molecules
Purity >98% (HPLC); NMR (Conforms)
Shipping Shipped Ambient
SMILES CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F
Solubility May be dissolved in DMSO (50 mg/ml)
Source Synthetic
Storage -20ºC

Safinamide is a selective and reversible monoamine oxidase B (MAO-B) inhibitor with additional anticonvulsant and glutamate-modulating properties. It is approved for use in Parkinson’s disease and has shown neuroprotective effects in seizure and neurodegeneration models. Safinamide’s multimodal action makes it a promising candidate for treating motor and non-motor symptoms in neurodegenerative disorders.

Classification: Danger

GHS Hazard Statements:

  • H301
  • H318
  • H400
  • Precautionary Statement Codes
  • P264, P264+P265, P270, P273, P280, P301+P316, P305+P354+P338, P317, P321, P330, P391, P405, and P501

Safinamide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-625)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. MS Strolin Benedetti et al. 1994 J. Pharm. Pharmacol. 46:814
2. RG Fariello et al. 1998 J. Pharmacol. Exp. Ther. 285:397
3. R Maj et al.1998 Eur. J. Pharmacol. 8 359:27
4. F Gardoni et al. 2018 J. Pharmacol. Exp. Ther. 2018 367:442
5. C Caccia et al. 2006 Neurology 67(7 Suppl. 2):S18
6. AH Schapira et al. 2013 Eur. J. Neurol. 20:271

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