| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; FCE-26743; PNU-151774E; NW-1015 |
| Cas No. | |
| Form | White powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (50 mg/ml) |
| Source | Synthetic |
| Storage |
Safinamide is a selective and reversible monoamine oxidase B (MAO-B) inhibitor with additional anticonvulsant and glutamate-modulating properties. It is approved for use in Parkinson’s disease and has shown neuroprotective effects in seizure and neurodegeneration models. Safinamide’s multimodal action makes it a promising candidate for treating motor and non-motor symptoms in neurodegenerative disorders.
Classification: Danger
GHS Hazard Statements:
- H301
- H318
- H400
- Precautionary Statement Codes
- P264, P264+P265, P270, P273, P280, P301+P316, P305+P354+P338, P317, P321, P330, P391, P405, and P501
Safinamide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-625)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. RG Fariello et al. 1998 J. Pharmacol. Exp. Ther. 285:397
3. R Maj et al.1998 Eur. J. Pharmacol. 8 359:27
4. F Gardoni et al. 2018 J. Pharmacol. Exp. Ther. 2018 367:442
5. C Caccia et al. 2006 Neurology 67(7 Suppl. 2):S18
6. AH Schapira et al. 2013 Eur. J. Neurol. 20:271