| Field | Specification |
|---|---|
| Applications | |
| Molecular weight | |
| Molecular formula | C24H22ClN3O2S |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
SARS-CoV-2 3CLpro-IN-19 is a non-covalent, non-peptide inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 0.7 μM. It shows broad-spectrum activity against Omicron subvariants BA.5, BQ.1.1 and XBB.1.5 infection in human cells, with EC50 values of 30-69 nM[1]. It has a molecular formula of C24H22ClN3O2S and a molecular weight of 451.97 g/mol.
Physical & Chemical Properties
| Molecular Formula | C24H22ClN3O2S |
|---|---|
| Molecular Weight | 451.97 g/mol |
| SMILES | CN(C)C1=CC=C(N(C(CC2=C(C(O)=CC=C3)C3=CN=C2)=O)CC4=CC(Cl)=CS4)C=C1 |
| Signaling Pathway | Anti-infection |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
Activity & Target
0.7 μM (SARS-CoV-2 3CLpro)[1]
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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