SDH-IN-8

SKU:BHB21901442
Overview
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SDH-IN-8 (CAS 2757173-77-4) is a succinate dehydrogenase inhibitor. Relevant to Anti-infection research. Molecular formula C18H14Cl3F4N3O, molecular weight 470.68 g/mol.
CAS Number 2757173-77-4
Molecular Weight 470.68 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-149601-50MG 50 mg
HY-149601-100MG 100 mg
HY-149601-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 2757173-77-4
Applications
  • Functional Assay (In Vitro)
Molecular weight 470.68
Molecular formula C18H14Cl3F4N3O
SMILES O=C(C1=C(F)N(C)N=C1C(F)F)N(C2CC2)C/C(C3=CC=C(Cl)C=C3F)=C(Cl)\Cl
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-149601
Main SKU BHB21901442
Inhibitors

Compound Overview

SDH-IN-8 is a potent inhibitor of succinate dehydrogenase (SDH), showing an IC50 of 27 nM against the porcine enzyme. It also exhibits fungicidal properties[1]. Its molecular formula is C18H14Cl3F4N3O, with a molecular weight of 470.68 g/mol.

Physical & Chemical Properties

CAS Number 2757173-77-4
Molecular Formula C18H14Cl3F4N3O
Molecular Weight 470.68 g/mol
SMILES O=C(C1=C(F)N(C)N=C1C(F)F)N(C2CC2)C/C(C3=CC=C(Cl)C=C3F)=C(Cl)\Cl
Signaling Pathway Anti-infection
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Yuan-Hui Huang, et al. Structure-Based Discovery of New Succinate Dehydrogenase Inhibitors via Scaffold Hopping Strategy. J Agric Food Chem. 2023 Sep 22.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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