| Field | Specification |
|---|---|
| Applications | |
| Source | Marine — Marine microorganism; Microbial — mangrove fungus Xylaria sp. (no. 2508) |
| Molecular weight | |
| Molecular formula | C19H36N4O6 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
SIRT1 activator 1 is a derivative of the marine natural product xyloallenoide A isolated from the mangrove fungus Xylaria sp. It shows angiogenic activity in zebrafish and protects hEPC against AngII-induced senescence by increasing SIRT1 expression and balancing the AMPK/Akt signaling pathway[1]. It has the molecular formula C19H36N4O6 and a molecular weight of 416.51 g/mol.
Physical & Chemical Properties
| Molecular Formula | C19H36N4O6 |
|---|---|
| Molecular Weight | 416.51 g/mol |
| Structure Classification | Ketones, Aldehydes, Acids |
| SMILES | C[C@@H](NC([C@@H](NC([C@H](N)C(C)C)=O)CCCCNC(OC(C)(C)C)=O)=O)C(O)=O |
| Signaling Pathway | Cell Cycle/DNA Damage; Epigenetics |
| Initial Source | Marine — Marine microorganism; Microbial — mangrove fungus Xylaria sp. (no. 2508) |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Jing Yang, et al. Marine Compound Exerts Antiaging Effect in Human Endothelial Progenitor Cells via Increasing Sirtuin1 Expression. ACS Pharmacol. Transl. Sci. Publication Date:October 10, 2023
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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