| Field | Specification |
|---|---|
| Target | |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C24H23N3O4 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Sirtuin modulator 5 is a sirtuin-modulating agent that can activate SIRT1 with a DC50 value below 50 μM. It can be used to extend the lifespan of a cell and to study a range of conditions, including diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and diseases or disorders that would benefit from increased mitochondrial activity[1]. It has the molecular formula C24H23N3O4 (MW 417.46).
Physical & Chemical Properties
| CAS Number | 694469-31-3 |
|---|---|
| Molecular Formula | C24H23N3O4 |
| Molecular Weight | 417.46 g/mol |
| SMILES | O=C(C1=CC(OC)=C(C(OC)=C1)OC)NC2=CC=CC(C3=CN4C=CC=C(C)C4=N3)=C2 |
| Target | SIRT1 |
| Signaling Pathway | Cell Cycle/DNA Damage; Epigenetics |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
Activity & Target
|
SIRT1 <50 μM (DC50) |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Michael Milburn, et al. Patent. WO2006094236A1.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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