| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Skf-107457 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Skf 107457 (CAS 144285-77-8) is a research-grade small molecule supplied by TargetMol.
Alternative names: Skf-107457
Physical Properties
| CAS Number | 144285-77-8 |
|---|---|
| Molecular Formula | C28H46N6O7 |
| Molecular Weight | 578.71 g/mol |
| SMILES | COC(=O)(CH)(NC(=O)(CH)(NC(=O)CN(CH)(O)(CH)(CC1=CC=CC=C1)NC(=O)(CH)(C)N… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Skf 107457 is a hexapeptide substrate analog with the scissile bond being replaced by a hydroxyethylene isostere.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Try the following steps: (1) warm the DMSO solvent to 37–50 °C before adding the compound; (2) vortex vigorously for 30 seconds then bath-sonicate for 1–2 minutes; (3) if still undissolved, prepare a more dilute stock. Note that maximum solubility values are reference conditions — actual solubility can vary with temperature, solvent lot, and compound batch. Contact BioHippo support if dissolution problems persist.
sonication can accelerate dissolution. If the compound is not dissolving, sonication is recommended. If you don't have an ultrasound machine, a lower solvent concentration or using less powder are recommended.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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