| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 1-{2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl}-1H-imidazole hydrochloride (1:1) |
| Cas No. | |
| Form | White solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in water |
| Source | Synthetic |
| Storage |
SKF-96365 is a selective inhibitor of receptor-mediated and voltage-gated calcium entry. It also inhibits cytochrome P450-mediated reactions and can reversibly activate non-selective cation channels in endothelial cells. In neuroscience, SKF-96365 is used to explore calcium signaling, neurovascular coupling, and the regulation of intracellular calcium dynamics in neurons and glial cells.
Classification: Irritant. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H315-H319-H335
Precautionary Phrases:
P261-P305 + P351 + P338
SKF-96365 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-305)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. Sheets J.J., Mason J.I., Wise C.A. and Eastabrook R.W. (1986) Biochem Pharmacol. 35: 487-491.
3. Schwarz G., Droogmans G. and Nilius B. (1994) Cell Calcium. 15: 45-54.
