SLC16A1 Antibody / Monocarboxylate transporter 1 / MCT1

SKU:BHA17136301
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NSJ Bioreagents
NSJ Bioreagents
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Overview
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Anti-SLC16A1 antibody from Rabbit, recombinant rabbit monoclonal, clone 20S76, Rabbit IgG. Recommended for workflows such as Western blot (WB), IHC-P. Reactivity: Human. Supplied as purified format.
Target SLC16A1
Clone Number 20S76
Host Rabbit
Reactivity Human
Application WB, IHC-P
Options selector
Catalog no. Formulation Size
RQ8882 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Formulation: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA; Size: 100 ul
  • Lead time: typically ships in ~2-3 business days; timing may vary by selected option.
  • Storage: The SLC16A1 antibody can be stored at -20oC.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No RQ8882
Clonality
  • Recombinant Rabbit Monoclonal
Host Rabbit
Immunogen A peptide sequence specific to Monocarboxylate transporter 1 protein was used as the immunogen for the SLC16A1 antibody.
Isotype
  • Rabbit IgG
Product Type
  • Antibodies
  • Primary Antibodies
Purity Affinity chromatography
Reactivity
  • Human
Storage The SLC16A1 antibody can be stored at -20oC.
Target SLC16A1
UniProt # P53985

Overview

SLC16A1 Antibody / Monocarboxylate transporter 1 / MCT1 is a anti-SLC16A1 Rabbit antibody Recombinant Rabbit Monoclonal clone 20S76 supplied in Purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Human. Reported localization: Cell membrane.

Key elements and design rationale

  • Target: SLC16A1
  • Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 20S76, isotype Rabbit IgG
  • Format: Purified
  • Applications (as listed): WB, IHC-P

Biological background

SLC16A1 (also called Monocarboxylate transporter 1 and MCT1) is a 12-transmembrane monocarboxylate/proton symporter that mediates bidirectional transport of lactate, pyruvate, and ketone bodies across the plasma membrane. Coupled to H+ gradients and aided by the chaperone basigin/CD147, SLC16A1 maintains cellular redox balance, supports glycolysis-oxidative coupling between cells, and contributes to pH homeostasis in metabolically active tissues.

SLC16A1 is broadly expressed, with high levels in skeletal muscle, cardiac muscle, erythrocytes, endothelium, and select immune and epithelial cells. Its activity underlies lactate shuttle biology and metabolic symbiosis, making it a useful readout in studies of exercise physiology, hypoxia responses, and metabolic remodeling under defined experimental conditions.

The SLC16A1 antibody enables specific detection of endogenous MCT1 in applications such as western blot, immunofluorescence, immunohistochemistry, and flow cytometry. Researchers use the SLC16A1 antibody from

Research relevance and current trends

  • Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
  • Considering isoforms and post-translational regulation when interpreting protein-level changes.
  • Comparing results across species and model systems with matched controls.

Common research applications

  • Western blotting: compare relative abundance and activation-state changes across conditions.
  • Immunohistochemistry: map target signal in tissue context and compare regions/phenotypes.

Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.

Notes for experimental interpretation

  • Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
  • Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.

Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today