| Field | Specification |
|---|---|
| Target | |
| Alternative names | Excitatory amino acid transporter 2|Glutamate/aspartate transporter II|Sodium-dependent glutamate/aspartate transporter 2|Solute carrier family 1 member 2|SLC1A2|EAAT2|GLT1 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | solute carrier family 1(glial high affinity glutamate transporter), member 2 |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
EAAT2 (also known as GLT-1), is encoded by SLC1A2 and is a glutamate transporter which can clear the majority of extracellular glutamate in brain and prevent brain seizures.Three isoforms of EAAT2 exist due to the alternative splicing. In addition to the 65-70 kDa monomer form, 120-140 kDa dimer of EAAT2 can also be observed on SDS-PAGE. (PMID: 22114258)
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes SLC1A2. It is validated for ELISA, Western Blot, Immunohistochemistry.
Validated Applications
| Applications | ELISA, Western Blot, Immunohistochemistry |
|---|---|
| WB | 1:500-1:2000 |
| IHC | 1:20-1:200 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
solute carrier family 1(glial high affinity glutamate transporter), member 2
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Immunogen | solute carrier family 1(glial high affinity glutamate transporter), member 2 |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 60-70 kDa, 120 kDa |
| UniProt # | P43004 |
| Gene ID | 6506 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Excitatory amino acid transporter 2|Glutamate/aspartate transporter II|Sodium-dependent glutamate/aspartate transporter 2|Solute carrier family 1 member 2|SLC1A2|EAAT2|GLT1 |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for SLC1A2 research from Fine Test, or contact us for alternative formats.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Kainic Acid-Induced Excitotoxicity Leads to the Activation of Heat Shock Response. Molecular Neurobiology (2023) [IF: 5.1] View Article
The Regulation of GLT-1 Degradation Pathway by SIRT4. Neurochemical Research (2023) [IF: 4.414] View Article