SLUG Antibody

SKU:BHA17101115
Suppliers
NSJ Bioreagents
NSJ Bioreagents
Details Products
Overview
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Anti-SLUG polyclonal antibody (Rabbit Ig) for target detection, validation, and assay development. Reactivity: Human; purified reagent to support WB and ELISA.
Target SLUG
Host Rabbit
Isotype Rabbit Ig
Reactivity Human
Application(s) WB, ELISA
Options selector
Catalog no. Formulation Size
F47912-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options (Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide; Size (2) — 0.08 ml, 0.4 ml)
  • Lead time: options listed as “In Stock at Manufacturer” typically ship after a short processing time (2–3 days). Timing may vary by fulfillment source.
  • Storage: Refer to the product datasheet for storage and handling.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: follow the product datasheet storage instructions.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No F47912
Clonality
  • Polyclonal (rabbit origin)
Host Rabbit
Immunogen A portion of amino acids 1-30 from the human protein was used as the immunogen for this SLUG antibody.
Isotype
  • Rabbit Ig
Product Type
  • Antibodies
  • Primary Antibodies
Purity Purified
Reactivity
  • Human
Storage Aliquot the SLUG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target SLUG
UniProt # O43623
SNAI2/SLUG is a transcriptional repressor that modulates both activator-dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved in the regulation of ITGB1 and ITGB4 expression and cell adhesion and proliferation in epidermal keratinocytes. Binds to E-box2 domain of BSG and activates its expression during TGFB1-induced epithelial-mesenchymal transition (EMT) in hepatocytes. Represses E-Cadherin/CDH1 transcription via E-box elements. Involved in osteoblast maturation. Binds to RUNX2 and SOC9 promoters and may act as a positive and negative transcription regulator, respectively, in osteoblasts. Binds to CXCL12 promoter via E-box regions in mesenchymal stem cells and osteoblasts. Plays an essential role in TWIST1-induced EMT and its ability to promote invasion and metastasis. [UniProt]
  • Format: Purified
  • Predicted species reactivity: Bovine, Mouse, Rat

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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