| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C22H17ClN2O2S2 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
SP4e is a PPAR-γ activator with an EC50 of 739 nM in HK-2 cells. In Swiss albino mice, it reduces blood glucose levels and lipid peroxidation while increasing glutathione levels and catalase activity[1]. It is supplied as a light yellow to yellow solid (C22H17ClN2O2S2, MW 440.97) at 99.72% purity.
Physical & Chemical Properties
| CAS Number | 3086376-12-4 |
|---|---|
| Molecular Formula | C22H17ClN2O2S2 |
| Molecular Weight | 440.97 g/mol |
| Purity | 99.72% |
| Appearance | Solid |
| Color | Light yellow to yellow |
| SMILES | ClC1=CC=CC=C1NC2=CC=C(S2)/C=C(C(N3CC4=CC=C(C=C4)C)=O)\SC3=O |
| Signaling Pathway | Cell Cycle/DNA Damage; Vitamin D Related/Nuclear Receptor; Metabolic Enzyme/Protease |
| Storage | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
Activity & Target
739 nM (PPAR-γ in the HK-2 cells)[1]
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
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