Spermine(N3BBB)

SKU:BHB21901545
Research Validated
Overview
Click light‑blue chips for details
Spermine(N3BBB) (CAS 1190203-80-5) is an ADC linker supplied as an oil. Relevant to Antibody-Drug Conjugate/ADC Related research. Molecular formula C25H48N6O6, molecular weight 528.69 g/mol.
Purity 95.60%
CAS Number 1190203-80-5
Molecular Weight 528.69 g/mol
Form Oil
Storage -20°C as supplied; in solvent -80°C
Options selector
Catalog no. Size
HY-151657-5MG 5 mg
HY-151657-10MG 10 mg
HY-151657-25MG 25 mg
HY-151657-50MG 50 mg
HY-151657-100MG 100 mg
HY-151657-200MG 200 mg
HY-151657-500MG 500 mg
HY-151657-1MLX10MM 1 mL x 10 mM (in DMSO)
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 mL x 10 mM (in DMSO)
  • Lead time: varies by selected option.
  • Storage: -20°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: transfer to -20°C as soon as possible.
Field Specification
CAS no. 1190203-80-5
Applications
  • Functional Assay (In Vitro)
Molecular weight 528.69
Molecular formula C25H48N6O6
Purity 95.60%
SMILES [N-]=[N+]=NCCCN(CCCCN(CCCNC(OC(C)(C)C)=O)C(OC(C)(C)C)=O)C(OC(C)(C)C)=O
Form Oil
Storage -20°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-151657
Main SKU BHB21901545
ADC Linkers & Payloads

Compound Overview

Spermine(N3BBB) is a tri-Boc-protected azido-spermine reagent used for multi-functionalization of pseudo-glycodendrimers via click reaction[1]. It is supplied as a colorless to light yellow oil (C25H48N6O6, MW 528.69) at 95.60% purity.

Physical & Chemical Properties

CAS Number 1190203-80-5
Molecular Formula C25H48N6O6
Molecular Weight 528.69 g/mol
Purity 95.60%
Appearance Oil
Color Colorless to light yellow
SMILES [N-]=[N+]=NCCCN(CCCCN(CCCNC(OC(C)(C)C)=O)C(OC(C)(C)C)=O)C(OC(C)(C)C)=O
Signaling Pathway Antibody-Drug Conjugate/ADC Related
Solubility In Vitro: DMSO: 250 mg/mL (472.87 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage -20°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.

[1]. Kösterke T, et al. Molecular architectures of glycosylated dendronized bottle brushes in action: Biocompatibility and anti-amyloidogenic activity of pseudo-glycodendrimers. Mater Today Bio. 2025;32:101771. Published 2025 May 10.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

In Vitro

SolventSolubilityNotes
DMSO250 mg/mL (472.87 mM)requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility)

Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); protect from light; avoid repeated freeze-thaw cycles.

Data provided by the manufacturer.

In Vitro

Pseudoglycodendrimers are highly branched, nanoscale synthetic macromolecules whose defining feature is that they mimic the structure and function of natural cell surface glycoconjugates using non-natural backbones (such as polyamidoamine, polycarboxylic acid, etc.). Typically, these molecules are built from a core at the center, highly branched internal repeating units (dendrons) and surface-modified carbohydrate termini, and they exhibit a highly symmetric spherical topological structure.

Data provided by the manufacturer.

Q.Why is there no price on some sizes?
A.Availability and lead time for those sizes are confirmed on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

Molecular architectures of glycosylated dendronized bottle brushes in action: Biocompatibility and anti-amyloidogenic activity of pseudo-glycodendrimers. Mater Today Bio 2025 May 10:32:101771. PMID: 40496726

Get a Quote

Please use this form for bulk quantity requests or customized products.

Contact Information

Product Information

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today