| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Product Type | |
| Signaling Pathway | |
| Target |
Compound Overview
Sphingomyelin (chicken egg) (CAS 383907-87-7) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 383907-87-7 |
|---|---|
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Sphingomyelins (SMs) are bioactive sphingolipids present in the cell membranes of mammals, constituting 2-15% of the total cellular phospholipid content, with higher concentrations in the brain and myelin sheaths of peripheral nerves. These compounds play a crucial role in modulating cholesterol distribution and maintaining cellular cholesterol balance. SMs are hydrolyzed by sphingomyelinase into ceramides, key sphingolipid signaling molecules. The product contains SM species predominantly with C16:0 fatty acyl chain lengths and may exhibit variations in its sphingoid backbone due to its natural origin. (Matreya, LLC. Catalog No. 1332)
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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