| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | [(E,2S,3R)-2-Amino-3-hydroxyoctadec-4-enyl] dihydrogen phosphate |
| Cas No. | |
| Form | White solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Sparingly soluble in 1:1 ethanol:water. Addition of small amounts of acetic acid may help dissolve this product. Soluble in warm methanol. |
| Source | Synthetic |
| Storage |
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that signals through a family of G-protein-coupled receptors (S1PR1–S1PR5) to regulate cell survival, migration, and immune responses. In the nervous system, S1P plays a critical role in neurogenesis, synaptic transmission, and neuroinflammation. Dysregulation of S1P signaling has been implicated in multiple sclerosis, Alzheimer’s disease, and stroke. Therapeutic agents targeting S1P receptors, such as fingolimod, have demonstrated efficacy in modulating neuroimmune interactions. S1P is also involved in maintaining blood-brain barrier integrity and neuronal-glial communication, making it a key molecule in neurodegenerative disease research.
Classification: Caution. Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S24/25 - Avoid contact with skin and eyes
Hazard Phrases:
- H315 - Causes skin irritation.
- H319 - Causes serious eye irritation.
- H335 - May cause respiratory irritation.
Precautionary Phrases:
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280 Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
- P321 Specific treatment (see on this label).
- P405 Store locked up.
- P501 Dispose of contents/container in accordance with local/regional/national/international regulations
Sphingosine-1-phosphate, D-erythro (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-386)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
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