| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol |
| Cas No. | |
| Form | Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in DMSO |
| Source | Synthetic |
| Storage |
Sphingosine is a bioactive lipid and precursor to ceramide and sphingosine-1-phosphate, both of which are critical regulators of cell fate. In the nervous system, sphingosine modulates signaling pathways involved in neuroinflammation, apoptosis, and synaptic function. It selectively inhibits protein kinase C and calmodulin-dependent enzymes, influencing neurotransmission and neuronal survival. Alterations in sphingolipid metabolism are associated with neurodegenerative diseases such as multiple sclerosis and Alzheimer's disease, making sphingosine a molecule of interest in neurobiology.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Sphingosine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-202)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Carter H.E., Glick F.J., Norris W.P., Phillips G.E. (1947) J Biol Chem. 170: 285-295.
