| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Source | Microbial — Phoma sp. C2932 |
| Molecular weight | |
| Molecular formula | C25H30O13 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Squalestatin 3 is a secondary metabolite that can be isolated from Phoma and inhibits squalene synthase with an IC50 of 6 nM[1]. It has the molecular formula C25H30O13 and a molecular weight of 538.50 g/mol, and the manufacturer notes it is derived from Phoma sp. C2932.
Physical & Chemical Properties
| CAS Number | 142505-92-8 |
|---|---|
| Molecular Formula | C25H30O13 |
| Molecular Weight | 538.50 g/mol |
| Structure Classification | Others |
| SMILES | OC([C@@]12[C@@](O)([C@H](O[C@@]([C@H](O)[C@H]2O)(CCC([C@@H](OC(C)=O)[C@H](C)CC3=CC=CC=C3)=C)O1)C(O)=O)C(O)=O)=O |
| Signaling Pathway | Metabolic Enzyme/Protease |
| Initial Source | Microbial — Phoma sp. C2932 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Watson N S, et al. The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety[J]. Bioorganic & Medicinal Chemistry Letters, 1993, 3(12): 2541-2546.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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