| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide |
| Cas No. | |
| Form | Off-white solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl |
| Source | Synthetic |
| Storage |
SRPIN340 is a selective inhibitor of serine–arginine protein kinases (SRPKs), particularly SRPK1 and SRPK2. These kinases regulate alternative splicing of pre-mRNA, a process increasingly recognized in neurodegenerative disease mechanisms. SRPIN340 has been used to study the role of aberrant splicing in diseases such as ALS and frontotemporal dementia. Its ability to modulate splicing events makes it a promising tool for investigating RNA-based pathologies in the nervous system.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
SRPIN340 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-514)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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