| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (2S,3R,4R,6R)-3-Methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one |
| Cas No. | |
| Form | Pale Yellow Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 50 mM in DMSO |
| Source | Synthetic |
| Storage |
Staurosporine is a broad-spectrum protein kinase inhibitor with high affinity for ATP-binding sites of numerous kinases. It is widely used in neuroscience research to induce apoptosis and study cell death pathways. Staurosporine's ability to trigger caspase activation and mitochondrial dysfunction makes it a standard tool for modeling neurodegeneration in vitro. Despite its lack of selectivity, it remains a cornerstone compound for dissecting kinase-dependent signaling in neuronal cells.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H340- H350
Precautionary Phrases:
P201-P308 + P313
Staurosporine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-253)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. Karaman M.W., et al. (2008) Nat. Biotechnol. 26(1): 127-132.
