| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt, SU 011248, SU 11248, SU112248 |
| Cas No. | |
| Form | Yellow solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (40 mg/ml) |
| Source | Synthetic |
| Storage |
Sunitinib malate is a receptor tyrosine kinase inhibitor that targets multiple kinases including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-α, PDGFR-β, KIT, FLT3, CSF-1R, and RET. In neuroscience, Sunitinib is used to study neurovascular signaling, glial activation, and neuroinflammation. Its broad-spectrum kinase inhibition profile makes it suitable for exploring the interplay between angiogenesis, immune responses, and neuronal survival in neurodegenerative disease models. Sunitinib is also being investigated for its potential to modulate blood-brain barrier function and tumor angiogenesis in brain cancers.
Classification: Reproductive toxicity (Category 1B), H360
Specific target organ toxicity-repeated exposure, Oral (Category 1), H372
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
- H360 May damage fertility or the unborn child.
- H372 Causes damage to organs through prolonged or repeated exposure if swallowed.
Precautionary statements:
- P201 Obtain special instructions before use.
- P202 Do not handle until all safety precautions have been read and understood.
- P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
- P264 Wash skin thoroughly after handling.
- P270 Do not eat, drink or smoke when using this product.
- P281 Use personal protective equipment as required.
- P308 + P313 IF exposed or concerned: Get medical advice/ attention.
- P405 Store locked up.
Sunitinib malate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-482)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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