| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A peptide sequence specific to TAR DNA binding protein 43 was used as the immunogen for the TARDBP antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
TARDBP Antibody / TAR DNA binding protein 43 / TDP43 is a anti-TARDBP Rabbit antibody Recombinant Rabbit Monoclonal clone ABAB-20 supplied in Purified format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human, Mouse, Rat. Reported localization: Nuclear, cytoplasmic.
Key elements and design rationale
- Target: TARDBP
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone ABAB-20, isotype Rabbit IgG
- Format: Purified
- Applications (as listed): WB
Biological background
TDP-43 participates in stress-responsive ribonucleoprotein remodeling and interacts with components of transcription, splicing, and translation pathways. Changes in localization, solubility, or post-translational status are widely monitored as readouts in studies of RNA metabolism, proteostasis, and cellular stress adaptation across model systems.
The TARDBP antibody enables specific detection of endogenous TDP-43 in applications such as western blot, immunofluorescence, immunohistochemistry, and immunoprecipitation. Researchers use the TARDBP antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
