| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C15H9F6N5 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
TAS2R14 agonist-1 is a potent partial agonist of TAS2R14, with an EC50 of 116.6 ± 23.6 nM[1]. It has a molecular formula of C15H9F6N5 and a molecular weight of 373.26 g/mol.
Physical & Chemical Properties
| CAS Number | 2439115-08-7 |
|---|---|
| Molecular Formula | C15H9F6N5 |
| Molecular Weight | 373.26 g/mol |
| SMILES | FC(C1=CC(C(F)(F)F)=CC(NC2=CC=CC=C2C3=NNN=N3)=C1)(F)F |
| Signaling Pathway | GPCR/G Protein |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
IC50 & Target
IC50: 116.6 nM (TAS2R14)[1]
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
In IP1 and cAMP assays, TAS2R14 agonist activates TAS2R14, with EC50 values of 100 nM for IP1 accumulation and 180 nM for cAMP accumulation, respectively.
Data provided by the manufacturer.
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