| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Concentration | |
| Form | Lyophilized Powder |
| Product Type | |
| Purity | |
| Reconstitution | |
| Shipping | |
| Solubility | >100mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min). |
| Source | Synthetic |
| Storage | |
| Target |
Product details
- Chemical name: 2-aminoethanesulfonic acid.
- Also known as: 2-Aminoethylsulfonic acid, Tauphon
- CAS number: 107-35-7
- Molecular formula: C2H7NO3S.
- Purity: >99%
- Concentration: 0.05-5 mM.
- Form: Lyophilized Powder
- Solubility: >100mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
- Reconstitution: >100mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
- Shipping: Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
- Target: Glycine receptor, Taurine transporter
- Source: Synthetic
- Activity: Taurine is a Glycine receptor (GlyR) partial agonist (EC50=1.7 mM)1. It displaces [3H]Strychnine bound to GlyR α1 expressing 293 cells membrane fraction (Ki=170 µM)2.
- Alternative names: 2-Aminoethylsulfonic acid, Tauphon
Scientific background
Taurine (2-aminoethanesulfonic acid) is a β-amino acid, one of the most abundant free amino acids found in vertebrates. Taurine can be present in many tissues including brain, myocardium, and kidney. It plays an important role in several physiological processes including cardiac contraction, antioxidation, blunting of hypertension, bile acid conjugation, maintenance of calcium homeostasis, osmoregulation, and membrane stabilization.Taurine acts as an endogenous partial agonist at the inhibitory glycine receptor (GlyR)1,2.The glycine receptor is a member of the ligand-gated ion channel (LGIC) superfamily. The receptor mediates fast inhibitory neurotransmission in the mammalian spinal cord and parts of the brain3.
Lead time: 1-2 Business Days
Country of origin: Israel/IL
Applications key
Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.
Bioassay tested: Yes
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- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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