| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C33H37F3N4O6S |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
TC9-305 is a potent, selective inhibitor of apoptosis, with strong inhibitory activity against both Bim- and tBid-induced apoptosis (EC50 values of 0.42 μM and 0.23 μM, respectively). It can maintain mitochondrial membrane potential, reduce ROS production, prevent the release of cytochrome c, and block the upstream pathways of mitochondrial-mediated apoptosis, and it can be used for research on neurological disease such as stroke[1]. It has a molecular formula of C33H37F3N4O6S and a molecular weight of 674.73 g/mol.
Physical & Chemical Properties
| CAS Number | 2092914-16-2 |
|---|---|
| Molecular Formula | C33H37F3N4O6S |
| Molecular Weight | 674.73 g/mol |
| SMILES | O=C1C=CC(C2=NC(S(CCCC(NC34CC5CC(CC(C4)C5)C3)=O)(=O)=O)=NC(C(F)(F)F)=C2)=CN1CC6=CC=C(C(OC)=C6)OC |
| Signaling Pathway | Apoptosis; NF-κB; Metabolic Enzyme/Protease; Immunology/Inflammation |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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