| Field | Specification |
|---|---|
| Alternative names | 2,2,6,6-Tetramethylpiperidine 1-oxyl, 2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical, (2,2,6,6-Tetramethyl-1-piperidinyl)oxidanyl, 1,1,5,5-tetramethylpentamethylene nitroxide, 2,2,6,6-Tetramethylpiperidine-1-oxyl |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C9H18NO |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | May be dissolved in DMSO (100 mg/ml); or Ethanol (100 mg/ml) |
| SMILES | |
| InChIKey | |
| Form | Purple Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
TEMPO (2,2,6,6-Tetramethylpiperidine 1-oxyl) is a stable nitroxide radical widely used as a spin label and redox probe in biological systems. In neuroscience, TEMPO has been explored for its antioxidant properties and ability to scavenge reactive oxygen species. Its membrane-permeable nature allows it to modulate oxidative stress in neuronal cells, potentially protecting against neurodegeneration. TEMPO derivatives have also been investigated for their role in reducing mitochondrial dysfunction and inflammation, key contributors to neurodegenerative pathology.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R34- Causes Burns
Hazard Phrases:
H314
Precautionary Phrases:
P280-P305 + P351 + P338-P310
TEMPO (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-155)
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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