Tetrodotoxin

SKU:BHB11900380
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Tetrodotoxin is a research-grade small-molecule blocker of Sodium Channel supporting Neuroscience and Ion Channels research. Supplied as a white powder with 98% purity (CAS 4368-28-9, MW 319.27) dissolvable in buffer or distilled water as needed.; store at -20°C. For research use only.
Cas No. 4368-28-9
Molecular Formula C11H17N3O8
Purity ≥98% (HPLC); 100% (TLC)
Application Notes Sodium Channel Blocker
Options selector
Catalog no. Size
SIH-602-1MG 1 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-602
Activity
  • Blocker
Alternative Names Fugu poison, Maculotoxin, Spheroidine, Tarichatoxin, TTX
Cas No. 4368-28-9
Form White powder
Molecular Weight 319.27
Product Type
  • Biochemicals
  • Small Molecules
Purity ≥98% (HPLC); 100% (TLC)
Shipping Shipped Ambient
SMILES C(C1(C2C3C(N=C(NC34C(C1OC(C4O)(O2)O)O)N)O)O)O
Solubility May be dissolved in buffer or distilled water as needed.
Source Synthetic
Storage -20ºC

Tetrodotoxin is a potent, selective, and reversible use-dependent inhibitor of voltage-gated sodium channels. Its ability to block neuronal action potentials makes it a valuable tool in neuroscience research, particularly for studying neuronal excitability, pain pathways, and ion channel function. Tetrodotoxin is frequently used in electrophysiological experiments to isolate specific neural responses and investigate the role of sodium channels in neurodegenerative diseases such as ALS and epilepsy.

Classification: Severe poison. H300 Fatal if swallowed

H310 Fatal in contact with skin

H330 Fatal if inhaled

Precautionary statement(s):

  • P260 Do not breathe dust/fume/gas/mist/vapours/spray
  • P262 Do not get in eyes, on skin, or on clothing
  • P264 Wash hands thoroughly after handling
  • P280 Wear protective gloves/protective clothing/eye protection/face protection
  • P284 Wear respiratory protection
  • P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
  • P302+350 IF ON SKIN: Gently wash with soap and water
  • P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing

Tetrodotoxin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-602)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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