| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C81H158N3O15P |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
TLR4 agonist-1 is a potent agonist of Toll-like receptor 4 (TLR4). It induces production of MIP-1β in RAW 264.7 and MM6 cells[1]. It has a molecular formula of C81H158N3O15P and a molecular weight of 1445.11 g/mol.
Physical & Chemical Properties
| CAS Number | 2374139-51-0 |
|---|---|
| Molecular Formula | C81H158N3O15P |
| Molecular Weight | 1445.11 g/mol |
| SMILES | OC[C@H]1O[C@@H](OC[C@@H](C(O)=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@@H]1OP(O)(O)=O |
| Signaling Pathway | Immunology/Inflammation |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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Liquiritin attenuates IONI-induced trigeminal neuropathic pain via TLR4/MyD88-dependent modulation of microglial M1-like polarization. Int Immunopharmacol 2026 May 15:177:116554. PMID: 41880679
