| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 5-(Tetradecyloxy)-2-furoic acid, RMI-14514, 5-tetradecoxyfuran-2-carboxylic acid |
| Cas No. | |
| Form | White crystalline powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (15 mg/ml); or ethanol (9 mg/ml) |
| Source | Synthetic |
| Storage |
TOFA is an acetyl-CoA carboxylase (ACC) inhibitor that disrupts fatty acid synthesis. While not widely cited in neurodegenerative disease research, TOFA is frequently used in metabolic and cancer biology to study lipid metabolism. Its relevance to neuroscience may emerge through investigations into lipid dysregulation in neurodegenerative disorders, where altered lipid synthesis and energy metabolism contribute to disease progression.
WHMIS Classification: Not WHMIS controlled.
Not a dangerous substance according to GHS.
Health hazard:
0
Flammability:
0
Physical hazards:
0
Potential Health Effects: Inhalation - May be harmful if inhaled. May cause respiratory tract irritation.
Skin - May be harmful if absorbed through skin. May cause skin irritation.
Eyes - May cause eye irritation.
Ingestion - May be harmful if swallowed.
TOFA (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-555)
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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