Topoisomerase I inhibitor 9

SKU:BHB21902180
Overview
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Topoisomerase I inhibitor 9 (CAS 1228150-86-4) is an inhibitor. Relevant to Cell Cycle/DNA Damage research. Molecular formula C23H15Br2FN2, molecular weight 498.19 g/mol.
CAS Number 1228150-86-4
Molecular Weight 498.19 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-156462-50MG 50 mg
HY-156462-100MG 100 mg
HY-156462-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 1228150-86-4
Applications
  • Functional Assay (In Vitro)
Molecular weight 498.19
Molecular formula C23H15Br2FN2
SMILES FC1=CC=C(C(C2=CNC3=C2C=C(Br)C=C3)C4=CNC5=C4C=C(Br)C=C5)C=C1
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-156462
Main SKU BHB21902180
Inhibitors

Compound Overview

Topoisomerase I inhibitor 9 inhibits leishmanial topoisomerase IB. It has antileishmanial activity against L. donovani promastigotes, with an IC50 of 34.81 μM[1]. It has a molecular formula of C23H15Br2FN2 and a molecular weight of 498.19 g/mol.

Physical & Chemical Properties

CAS Number 1228150-86-4
Molecular Formula C23H15Br2FN2
Molecular Weight 498.19 g/mol
SMILES FC1=CC=C(C(C2=CNC3=C2C=C(Br)C=C3)C4=CNC5=C4C=C(Br)C=C5)C=C1
Signaling Pathway Cell Cycle/DNA Damage
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Biological Activity

Activity & Target

34.81 μM[1]

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Kour P, et al. Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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