Topramezone

SKU:BHB20440985
Overview
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Topramezone (CAS 210631-68-8) is a small molecule inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Small Molecule Inhibitor
CAS No. 210631-68-8
Molecular Weight 363.39
Form Solid
Shipping Room Temperature
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 50 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Options selector
Catalog no. Size
T74369-5MG 5 mg
T74369-50MG 50 mg
Field Specification
Activity
  • Small Molecule Inhibitor
Cas No. 210631-68-8
Molecular Weight 363.39
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Others
SMILES Cc1c(ccc(c1C1=NOCC1)S(C)(=O)=O)C(=O)c1cnn(C)c1O
Target Others

Compound Overview

Topramezone (CAS 210631-68-8) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 210631-68-8
Molecular Formula C16H17N3O5S
Molecular Weight 363.39 g/mol
SMILES Cc1c(ccc(c1C1=NOCC1)S(C)(=O)=O)C(=O)c1cnn(C)c1O
Form Solid
Shipping Room Temperature (RT)

Biological Activity

Topramezone, a highly effective 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor, functions as a herbicide for the post-emergence eradication of broadleaf and grass weeds in corn (1).

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

What should I do if the products in powder form adhere to the vial tightly?

Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.

How long does sonication usually take?

Sonication time depends on compound solubility and concentration. In most cases, 1–3 minutes of intermittent bath sonication is sufficient to dissolve small molecule compounds in DMSO. For poorly soluble compounds, warming the solvent to 37–50 °C combined with brief vortexing between sonication pulses can improve dissolution. If the compound remains undissolved, prepare a more dilute stock solution.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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