| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | N-(4-Chloro-3-oxo-1-phenyl-2-butanyl)-4-methylbenzenesulfonamide |
| Cas No. | |
| Form | White Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (>10 mg/ml) and in 10 mM in methanol and ethanol (50 mg/ml) |
| Source | Synthetic |
| Storage |
TPCK (Tosyl phenylalanyl chloromethyl ketone) is a protease inhibitor known to target serine and cysteine proteases. In neuroscience, TPCK is utilized to study protease-mediated signaling pathways and neuroinflammation. Its ability to inhibit specific proteases makes it a valuable tool in dissecting mechanisms of neuronal apoptosis and neurodegenerative cascades.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
37/38-41
Hazard Phrases:
H315-H318-H335
Precautionary Phrases:
P261-P280-P305 + P351 + P338
TPCK (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-207)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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