| Field | Specification |
|---|---|
| Alternative names | (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C11H17N3O |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml) |
| SMILES | |
| InChIKey | |
| Form | Oil dissolved in DMSO (1mg/ml) |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Triacsin C is a potent inhibitor of long-chain fatty acyl-CoA synthetase, an enzyme involved in lipid metabolism. By blocking the synthesis of triglycerides, diglycerides, and cholesterol esters, Triacsin C disrupts lipid signaling pathways implicated in neurodegeneration. It has been shown to prevent beta-cell apoptosis and exhibits vasodilatory properties. In the context of neuroscience, Triacsin C is used to study the role of lipid metabolism in neuronal survival, inflammation, and synaptic function, particularly in diseases like Alzheimer's and Parkinson's.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Triacsin C (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-203)
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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