Trimebutine

SKU:BHB20400707
Overview
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Trimebutine (CAS 39133-31-8) is a receptor agonist supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Receptor Agonist
CAS No. 39133-31-8
Molecular Weight 387.47 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T0918-1MLX10MM 1 mL x 10 mM (in DMSO)
T0918-1G 1 g
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mL x 10 mM (in DMSO), 1 g
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T0918
Activity
  • Receptor Agonist
Alternative Names Mebutin
Cas No. 39133-31-8
Molecular Weight 387.47
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Endocrinology/Hormones///GPCR/G Protein///Neuroscience
SMILES C(COC(=O)C1=CC(OC)=C(OC)C(OC)=C1)(N(C)C)(CC)C2=CC=CC=C2
Target Opioid Receptor

Compound Overview

Trimebutine (CAS 39133-31-8) is a research-grade small molecule supplied by TargetMol.

Alternative names: Mebutin

Physical Properties

CAS Number 39133-31-8
Molecular Formula C22H29NO5
Molecular Weight 387.47 g/mol
SMILES C(COC(=O)C1=CC(OC)=C(OC)C(OC)=C1)(N(C)C)(CC)C2=CC=CC=C2
Form Solid
Shipping Room Temperature (RT)

Biological Activity

Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders. It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. Trimebutine is not an FDA-Approved/Clinical drug, but it is available in Canada and several other international countries.

Target(s): Opioid Receptor

Signaling pathway(s): Endocrinology/Hormones, GPCR/G Protein, Neuroscience

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Does the product need to be protected from light?

Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.

What do "mg/mL" and "mM" mean?

mg/mL (milligrams per milliliter) and mM (millimolar = millimoles per liter) are two concentration units for the same solution. To convert: mM = (mg/mL × 1000) / MW (g/mol). For example, for a compound with MW = 350 g/mol: 1 mg/mL = 1000/350 = 2.86 mM. Use the molar concentration calculator on the TargetMol website for quick conversions.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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