| Field | Specification |
|---|---|
| Applications | |
| Molecular weight | |
| Molecular formula | C17H13ClN6OS |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Tubulin inhibitor 38 is a tetrazole-based tubulin inhibitor with antiproliferative activity. At 100 nM for 24 h it causes mitotic arrest, blocks the cell cycle at G2/M phase, and induces apoptosis, and it shows high cytotoxicity with a high selectivity index among HeLa, MCF7 and U87 MG cells[1]. It has the molecular formula C17H13ClN6OS and a molecular weight of 384.84 g/mol.
Physical & Chemical Properties
| Molecular Formula | C17H13ClN6OS |
|---|---|
| Molecular Weight | 384.84 g/mol |
| SMILES | ClC1=NC(SC)=CC(C2=NN=NN2C3=CC=C(N(C)C=C4C=O)C4=C3)=C1 |
| Signaling Pathway | Cell Cycle/DNA Damage; Cytoskeleton |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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