U-Blot® 53BP1 (Phospho Ser1778) Rabbit Polyclonal Antibody

SKU:BHA21804649
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-53BP1 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot with reactivity to Human, Rat, Mouse.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Rat, Mouse
Conjugate Unconjugated
Isotype IgG
Applications Western Blot
Options selector
Catalog no. Size
WP10281-50 50 uL
WP10281-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target 53BP1
Antigen
  • 53BP1 (Ser1778)
Alternative names Tumor suppressor p53-binding protein 1;53BP1;p53-binding protein 1;p53BP1
Gene ID 7158 (Human) | 27223 (Mouse)
Host Rabbit
Clonality
  • Polyclonal
Isotype
  • IgG
Reactivity
  • Human
  • Rat
  • Mouse
Applications
  • Western Blot
Immunogen Synthesized phosho peptide around human 53BP1 (Ser1778)
Conjugate
  • Unconjugated
Molecular weight Observed: 213 kDa
Purification Affinity Purified
Cellular localization Nucleus . Chromosome . Chromosome, centromere, kinetochore . Localizes to the nucleus in absence of DNA damage (PubMed:28241136). Following DNA damage, recruited to sites of DNA damage, such as double stand breaks (DSBs): recognizes and binds histone H2A monoubiquitinated at 'Lys-15' (H2AK15Ub) and histone H4 dimethylated at 'Lys-20' (H4K20me2), two histone marks that are present at DSBs sites (PubMed:23333306, PubMed:23760478, PubMed:24703952, PubMed:28241136, PubMed:17190600). Associated with kinetochores during mitosis (By similarity). .
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP10281
Main SKU BHA21804649
Antibody

Product Overview

U-Blot® 53BP1 (Phospho Ser1778) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against 53BP1. Recognizes Phospho. It has been validated for Western Blot and reacts with Human, Rat, Mouse.

Validated Applications

Target 53BP1
Host Rabbit
Clonality Polyclonal
Isotype IgG
Conjugate Unconjugated
Reactivity Human, Rat, Mouse
Applications Western Blot
Purification Affinity Purified
Specificity This antibody detects endogenous levels of Human 53BP1 (phospho-Ser1778)
Molecular Weight Observed: 213 kDa
UniProt / Swiss-Prot Q12888 (Human) | P70399 (Mouse)

Recommended dilutions: WB 1:1000-2000

Immunogen / Antigen

Synthesized phosho peptide around human 53BP1 (Ser1778)

Reactivity Notes

Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-2000

What species does it react with?

Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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