| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human Actin, Muscle Specific AA range: 2-50 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Actin, Muscle Specific (ABT-MSA) Mouse Monoclonal Antibody (WM1589) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Actin_Muscle Specific. It has been validated for Immunohistochemistry, ELISA and reacts with Human, Mouse, Rat, Monkey, Bovine, Pig, Chicken.
Validated Applications
| Target | Actin_Muscle Specific |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-MSA |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Monkey, Bovine, Pig, Chicken |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize proteins from smooth muscle, myocardium and skeletal muscle α actin and smooth muscle derived γ actin, and β actin or non smooth muscle derived γ actin does not respond. |
| Molecular Weight | Observed: 42 kDa |
| UniProt / Swiss-Prot | P68032;P68133;P63267;P62736 (Human) |
Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human Actin, Muscle Specific AA range: 2-50
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Monkey, Bovine, Pig, Chicken. Confirm suitability for untested species before use.
Scientific Background
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Confirmed reactivity: Human, Mouse, Rat, Monkey, Bovine, Pig, Chicken. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-MSA.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
