| Field | Specification |
|---|---|
| Target | |
| Alternative names | Acetaldehyde dehydrogenase 2;Aldehyde dehydrogenase 2 family;mitochondrial;Aldehyde dehydrogenase 2 family;Aldehyde dehydrogenase mitochondrial;Aldehyde dehydrogenase, mitochondrial;ALDH 2;ALDH class 2;ALDH E2;ALDH-E2;Aldh2;ALDH2_HUMAN;ALDHI;ALDM;Liver mitochondrial ALDH;MGC1806;Mitochondrial aldehyde dehydrogenase 2;MS767;Nucleus encoded mitochondrial aldehyde dehydrogenase 2. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human ALDH2 protein fragments expressed in E.coli |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® ALDH2 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against ALDH2. It has been validated for Western Blot and reacts with Human, Mouse, Rat, Monkey, Hamster.
Validated Applications
| Target | ALDH2 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Monkey, Hamster |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of ALDH2 and does not cross-react with related proteins. |
| Molecular Weight | Observed: 56 kDa |
| UniProt / Swiss-Prot | P05091 (Human) | P47738 (Mouse) |
Recommended dilutions: WB 1:1000
Immunogen / Antigen
Purified recombinant human ALDH2 protein fragments expressed in E.coli
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Monkey, Hamster. Confirm suitability for untested species before use.
Scientific Background
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000
Confirmed reactivity: Human, Mouse, Rat, Monkey, Hamster. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
