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Product Overview
U-Blot® ALKBH2 Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against ALKBH2. It has been validated for Western Blot, Flow Cytometry and reacts with Human, Mouse, Rat.
Validated Applications
| Target | ALKBH2 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT1116R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Flow Cytometry |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 29 kDa | Observed: 29 kDa |
| UniProt / Swiss-Prot | Q6NS38 (Human) | Q6P6J4 (Mouse) |
Recommended dilutions: WB 1:1000-1:5000;FC 1:100-1:500
Immunogen / Antigen
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 (Alkylated DNA repair protein alkB homolog 2) (DNA oxidative demethylase ALKBH2) (Oxy DC1)
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]
Safety & Handling
This antibody is validated for Western Blot, Flow Cytometry. Recommended dilutions: WB 1:1000-1:5000;FC 1:100-1:500
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT1116R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
